Eoin Reddan partners Jonathan Sexton at half back, while Gordon D'Arcy returns to the line up to partner Fergus McFadden at centre.
Isa Nacewa is named on a bench alongside the likes of Isaac Boss and Rhys Ruddock.
LEINSTER:
15: Rob Kearney
14: Dave Kearney
13: Fergus McFadden
12: Gordon D'Arcy
11: Andrew Conway
10: Jonathan Sexton
9: Eoin Reddan
1: Cian Healy
2: Sean Cronin
3: Mike Ross
4: Damian Browne
5: Devin Toner
6: Kevin McLaughlin
7: Sean O'Brien
8: Jamie Heaslip CAPTAIN
REPLACEMENTS:
16: Aaron Dundon
17: Heinke van der Merwe
18: Jamie Hagan
19: Rhys Ruddock
20: Leo Auva'a
21: Isaac Boss
22: Isa Nacewa
23: Fionn Carr
REFEREE: Marius Mitrea (FIR), ASSISTANT REFEREES: Neil Hennessy, Phil Fear (both WRU), TMO: Neil Ballard (WRU)