Leo Cullen leads an experienced Leinster side for the visit of the Ospreys. Cian Healy and Mike Ross come into the starting front row alongside John Fogarty, with Shane Jennings continuing in the back-row alongside fellow Ireland internationals Kevin McLaughlin and Jamie Heaslip.
Shaun Berne partners Eoin Reddan at half-back, while Gordon D'Arcy partners Bank of Ireland Player of the Month Fergus McFadden who will make his 15th appearance of the season. Girvan Dempsey starts at full-back in a back three which also includes Shane Horgan and Isa Nacewa.
The replacements bench will be confirmed closer to kick off.
Meanwhile, Friday sees Leinster's second 'Kid's Takeover' day which will see young supporters be involved in the running of match-day.
Tasks such as reading out the teams, delivering the match ball and interviews with some of the squad will see children taking over. There will also be 15 mascots and there will also be all the regular 'Family Day' activity including Tag rugby, the Leinster Skills roadshow and climbing wall. The Spinnies and Leo the Lion will also be on hand to help with the fun with face painting and giveaways.
To coincide with this, there are a range of family tickets available, with a family ticket covering 2 adults and 2 children starting from €50.
Over 15,000 tickets have now been sold for Friday's game and tickets are still on sale from www.leinsterrugby.ie and can be purchased from Ticketmaster outlets.
LEINSTER:
15: Girvan Dempsey
14: Shane Horgan
13: Fergus McFadden
12: Gordon D'Arcy
11: Isa Nacewa
10: Shaun Berne
9: Eoin Reddan
1: Cian Healy
2: John Fogarty
3: Mike Ross
4: Leo Cullen CAPTAIN
5: Nathan Hines
6: Kevin McLaughlin
7: Shane Jennings
8: Jamie Heaslip
REPLACEMENTS FROM: Richardt Strauss, Stan Wright, Malcolm O'Kelly, Stephen Keogh, Paul O'Donohoe, Eoin O'Malley, Andrew Conway, Simon Keogh
REFEREE: Peter Allan (SRU), ASSISTANT REFEREES: Leo Colgan (IRFU), Peter Roche (IRFU), 4th OFFICIAL: Brian Montayne (ARLB), 5th OFFICIAL: Danny Wallace (ARLB), TMO: Alan Rogan (IRFU)
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