Injuries forced coach Franco Bernini to change both centres. Gabriel Pizarro, who came from the bench in the first two league matches, will start alongside Gilberto Pavan, who will make his debut after spending the entire summer recovering from an injury.
Also South African speedy wing Danwel Demas will make his first appearance replacing Giulio Toniolatti. The last change regards the front row, with Alberto De Marchi and Salvatore Perugini switching their positions: De Marchi will play tighthead-prop, with Salvatore Perugini to return to his favourite position at loosehead-prop.
Other changes involved the bench, with Joshua Furno, Andrea Benatti, Giovanbattista Venditti and Riccardo Bocchino all at the first call of the season.
AIRONI
15 Julien Laharrague; 14 Danwel Demas, 13 Gilberto Pavan, 12 Gabriel Pizarro, 11 Giulio Rubini; 10 Ludovic Mercier, 9 Tito Tebaldi; 1 Salvatore Perugini, 2 Fabio Ongaro, 3 Alberto De Marchi; 4 Carlo Del Fava, 5 Quintin Geldenhuys (cap); 6 Jaco Erasmus, 7 Gareth Krause, 8 Nick Williams.
Bench: 16 Luca Redolfini, 17 Luigi Ferraro, 18 Andrea De Marchi, 19 Joshua Furno, 20 Andrea Benatti, 21 Pablo Canavosio, 22 Giovanbattista Venditti, 23 Riccardo Bocchino.