The Blues will look to build on the victory when they travel to the Irish capital but know it will be a big ask with their only previous victory in Dublin in the Magners League was 22-18 against Leinster at Donnybrook in March 2004.
There are three other changes in the pack to the starting XV that defeated Edinburgh with Tom Davies, Deiniol Jones and Sam Warburton all starting having been on the bench last weekend.
The only change in the backs sees Dafydd Hewitt coming in for Tom Shanklin at centre.
Cardiff Blues: 15 Chris Czekaj 14 Richard Mustoe 13 Casey Laulala 12 Dafydd Hewitt 11 Tom James 10 Dan Parks 9 Richie Rees 8 Xavier Rush (c) 7 Sam Warburton 6 Michael Paterson 5 Deiniol Jones 4 Bradley Davies 3 Scott Andrews 2 T Rhys Thomas 1 Tom Davies
Replacements: 16 Rhys Williams 17 John Yapp 18 Fa'ao Filise 19 James Down 20 Ben White 21 Lloyd Williams 22 Ceri Sweeney 23 Gavin Evans