Centre Keith Matthews will make his first start in the game, while Colm Rigney will mark his return to the province after two seasons with Leeds Tykes, starting at No 8.
On the bench Ronan Loughney, Daniel Riordan and hooker Chris Venter are all in line to make their competitive debuts.
Connacht: 15. David Slemen, 14. Conor McPhillips, 13. Darren Yapp, 12. Keith Matthews, 11. Matt Mostyn, 10. Paul Warwick, 9. Chris Keane; 1. Ray Hogan, 2. John Fogarty, 3. Stpehen Knoop, 4. Christian Short, 5. Andrew Farley, 6. John Muldoon, 7. Matt Lacey, 8. Colm Rigney.
Replacement: 16. Chris Venter, 17. Dan McFaland, 18. Ronan Loughney, 19. Michael Swift, 20. Brendan O'Connor, 21. Conor O'Loughlin, 22. Daniel Riordan.
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