Troy Nathan starts at full back with Gavin Duffy reverting to inside centre for the injured Niva Ta'auso and David Gannon comes in, in the backrow for Colm Rigney who picked up a knee injury against the Ospreys two weeks ago.
Johnny O'Connor has been named among the replacements having impressed in lasts week 'A' match against Ulster and Conor Muldoon is also named on the bench in place of the injured Adrian Flavin.
Connacht team:
T Nathan; L Bibo, G Duffy, K Matthews, F Carr; I Keatley, F Murphy; B Wilkinson, S Cronin, R Morris; A Browne, A Farley; D Gannon, R Ofisa, J Muldoon (C).
Replacements:
C Muldoon, R Loughney, M Swift, J O'Connor, C O'Loughlin, A Dunne, M Deane.
Not considered due to injury:
A Flavin (leg), B McGovern (ankle), C Rigney (knee), N Ta'auso (hamstring), A Wynne (jaw).
Guinness PRO12
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