Full-back Gavin Duffy will captain the side, while hooker Adrian Flavin will be vice-captain.
Centre Keith Matthews and flanker Johnny O'Connor return to the side after injury.
Connacht: Gavin Duffy (capt); Troy Nathan, Niva Ta'auso, Keith Matthews, Liam Bibo; Miah Nikora, Conor O'Loughlin; Brett Wilkinson, Adrian Flavin, Jamie Hagan; Michael Swift, Bernie Upton; Mike McComish, Johnny O'Connor, George Naoupu.
Replacements: Dermot Murphy, Ronan Loughney, Andrew Browne, Ray Ofisa, Ian Keatley, Kierran Campbell, Aidan Wynne.
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland