Ben Blair and Richie Rees have withdrawn from the squad, both suffering with their hamstrings. However, both players will be available for the Harlequins match.
Leigh Halfpenny moves from the bench to play at Fullback, while Darren Allinson replaces Richie Rees on the bench at Scrum Half.
Chris Czekaj moves onto the bench in place of Halfpenny.
Speaking ahead of the match Cardiff Blues Captain Paul Tito said,
"I've been impressed with what I've seen of Glasgow this season. I watched their match against the Ospreys last week and they scored a nice try and looked very dangerous."
"They have a very good set piece, a very solid line out, and I'm sure Dan Parks will be aiming to control things from fly half."
"They play a good kicking game, and put in high balls to put pressure on our catchers, so we have to be aware of those threats and be prepared for them."
"We lost heavily to them up there last season so will be looking to get one back on them today."
"Against the Scarlets I think we played well for 65 minutes, but it was disappointing to let them back in to the game for the last 15 which made the end of the match tense."
"However, we have to give credit to the Scarlets, they put some nice moves together and really threatened us, so we must make sure the same thing doesn't happen on Saturday."
Tickets for the match are available by calling the ticket office on 0845 345 1400 or buy online at cardiffblues.com/tickets
15 Ben Blair, 14 Richard Mustoe, 13 Tom Shanklin, 12 Gavin Evans, 11 Gareth Thomas, 10 Sam Norton-Knight, 9 Gareth Cooper
1 John Yapp, 2 Gareth Williams, 3 Gary Powell, 4 Deiniol Jones, 5 Paul Tito(c), 6 Sam Warburton, 7 Robin Sowden-Taylor, 8 Andy Powell
Replacements
16 Darren Morris, 17 Rhys Williams, 18 Bradley Davies, 19 Scott Morgan, 20 Richie Rees / Darren Allinson, 21 Ceri Sweeney, 22 Leigh Halfpenny
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland